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Cheap flight tickets from Chicago to Knoxville

Compare Chicago to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Chicago to Knoxville Airport

Looking for a cheap last-minute deal or the best return flight from Chicago to Knoxville Airport? If you want to travel next month, return fares start from RM898. Find the lowest prices on one-way and return tickets right here.
Knoxville.RM429 per passenger.Departing Thu, 9 Jul, returning Sun, 12 Jul.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Thu, 9 Jul, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Sun, 12 Jul, arriving in Chicago Midway.Price includes taxes and charges.From RM429, select.
Knoxville.RM476 per passenger.Departing Thu, 18 Jun, returning Sun, 21 Jun.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Thu, 18 Jun, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Sun, 21 Jun, arriving in Chicago Midway.Price includes taxes and charges.From RM476, select.
Knoxville.RM496 per passenger.Departing Thu, 18 Jun, returning Thu, 2 Jul.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Thu, 18 Jun, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Thu, 2 Jul, arriving in Chicago Midway.Price includes taxes and charges.From RM496, select.
Knoxville.RM521 per passenger.Departing Sun, 24 May, returning Thu, 28 May.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Sun, 24 May, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Thu, 28 May, arriving in Chicago Midway.Price includes taxes and charges.From RM521, select.
Knoxville.RM533 per passenger.Departing Sun, 24 May, returning Thu, 4 Jun.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Sun, 24 May, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Thu, 4 Jun, arriving in Chicago Midway.Price includes taxes and charges.From RM533, select.
Knoxville.RM898 per passenger.Departing Fri, 10 Apr, returning Sun, 12 Apr.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Fri, 10 Apr, arriving in Knoxville.Inbound direct flight with United departs from Knoxville on Sun, 12 Apr, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM898, select.
Knoxville.RM899 per passenger.Departing Fri, 14 Aug, returning Sat, 22 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago O'Hare International on Fri, 14 Aug, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 22 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM899, select.
Knoxville.RM902 per passenger.Departing Fri, 4 Sep, returning Mon, 7 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago Midway on Fri, 4 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 7 Sep, arriving in Chicago Midway.Price includes taxes and charges.From RM902, select.
Knoxville.RM993 per passenger.Departing Thu, 6 Aug, returning Sun, 9 Aug.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Thu, 6 Aug, arriving in Knoxville.Inbound direct flight with United departs from Knoxville on Sun, 9 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM993, select.
Knoxville.RM1,047 per passenger.Departing Tue, 31 Mar, returning Sun, 5 Apr.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Tue, 31 Mar, arriving in Knoxville.Inbound direct flight with United departs from Knoxville on Sun, 5 Apr, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,047, select.
Knoxville.RM1,090 per passenger.Departing Fri, 9 Oct, returning Mon, 12 Oct.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Chicago Midway on Fri, 9 Oct, arriving in Knoxville.Inbound direct flight with Allegiant Air departs from Knoxville on Mon, 12 Oct, arriving in Chicago Midway.Price includes taxes and charges.From RM1,090, select.
Knoxville.RM1,090 per passenger.Departing Wed, 25 Mar, returning Sat, 28 Mar.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Wed, 25 Mar, arriving in Knoxville.Inbound direct flight with United departs from Knoxville on Sat, 28 Mar, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,090, select.
Knoxville.RM1,205 per passenger.Departing Fri, 4 Sep, returning Mon, 7 Sep.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Fri, 4 Sep, arriving in Knoxville.Inbound direct flight with United departs from Knoxville on Mon, 7 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,205, select.
Knoxville.RM1,249 per passenger.Departing Sat, 28 Nov, returning Sun, 6 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago O'Hare International on Sat, 28 Nov, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sun, 6 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,249, select.
Knoxville.RM1,328 per passenger.Departing Sun, 1 Nov, returning Fri, 6 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago O'Hare International on Sun, 1 Nov, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Fri, 6 Nov, arriving in Chicago Midway.Price includes taxes and charges.From RM1,328, select.
Knoxville.RM1,351 per passenger.Departing Thu, 30 Apr, returning Tue, 5 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago O'Hare International on Thu, 30 Apr, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 5 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,351, select.

Find the cheapest month to fly from Chicago to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Knoxville flights are currently cheapest in July.
Mar
from RM1,090
Apr
from RM898
May
from RM521
Jun
from RM476
Jul
from RM429
Aug
from RM899
Sep
from RM902
Oct
from RM1,090
Nov
from RM1,328
Dec
Find prices
Jan
Find prices
Feb
Find prices

Direct flights from Chicago to Knoxville

Chicago to Knoxville: Alternative routes

Compare routes from Chicago to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from RM429
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Chicago to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundRM429
Cheapest month to flyJuly
Average flight time1 hr, 39 mins
Most popular airlineAmerican Airlines
Average flights per week297

Check out these Knoxville hotels

Ready to plan your stay? Other travellers rate these Knoxville hotels for cleanliness, service and location.
Drury Inn & Suites Knoxville West
16.52 km from city centre
RM634
Per night
Hyatt Place Knoxville/Downtown
0.13 km from city centre
RM824
Per night
Hampton Inn & Suites Knoxville/North I-75
7.23 km from city centre
RM544
Per night
Drury Inn & Suites Knoxville West
16.52 km from city centre
RM634
Per night
Hyatt Place Knoxville/Downtown
0.13 km from city centre
RM824
Per night
Hampton Inn & Suites Knoxville/North I-75
7.23 km from city centre
RM544
Per night
Explore top-rated hotels

Finding cheap flights from Chicago to Knoxville: Frequently asked questions

The best price we found for a return flight from Chicago to Knoxville is RM429. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 38 minutes is the average flight time from Chicago to Knoxville.
American Airlines, United and PSA Airlines fly direct from Chicago to Knoxville.
As of March 2026, there are 594 flights per week flying from Chicago to Knoxville.
The cheapest month to fly from Chicago to Knoxville is usually July.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Knoxville Airport on Thursday, 9 July 2026.
Yes – the average flight time is 1 hour and 38 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Knoxville is Allegiant Air .

Travelling from Chicago to McGhee Tyson Airport (TYS): What you need to know

  • Start your trip planning by checking out the best place to catch your flight from Chicago to McGhee Tyson Airport (TYS). Explore the options for setting off from O'Hare International Airport (ORD) or Chicago Midway International Airport (MDW), two of the city's main airports.

  • Expect to be travelling for 1 hour 45 minutes. That's the average duration of a direct Chicago to McGhee Tyson Airport flight.

  • McGhee Tyson Airport is located in Knoxville. The city runs on the UTC-4 timezone and is one hour ahead of Chicago.

  • With 50 direct weekly flights between the two airports, O'Hare International Airport (ORD) to McGhee Tyson Airport (TYS) is the most popular route. United Airlines operates the earliest flight at 7:15am. If you prefer to make the most of your day before jetting off, the latest flight from ORD to TYS is with United Airlines at 9:08pm.

  • Your flight from Chicago to TYS won't wait if you're late, so be at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead for international travel.

  • Delays at check-in and security are likely if you're heading away during high season, so give yourself some extra breathing space. The recommendation for peak periods? Get there up to four hours ahead for international flights and at least two hours for domestic departures.

Airports in Chicago

O'Hare International Airport (ORD)

  • Fly without interruptions from O'Hare International Airport (ORD). Direct flights from Chicago to McGhee Tyson Airport (TYS) are available from here.

  • You can get away on a direct flight from Chicago to McGhee Tyson Airport with United Airlines. This popular airline operates services from ORD.

  • The majority of passengers prefer to book seats with United Airlines from ORD to TYS.

  • United Airlines is the most punctual carrier on this route, with 76.67% of its services arriving as scheduled.

  • ORD is about 40 kilometres from central Chicago. If you're catching a cab, ride-sharing or driving from the centre, it'll take 35 minutes or so to get there, depending on the traffic. If you're using public transport, expect the trip time to be around 55 minutes.

  • In search of a comfortable hotel near O'Hare International Airport? If you've booked an early flight from Chicago to McGhee Tyson Airport, these accommodation options will have you sleeping moments from check-in:

  • Of the flights that depart from O'Hare International Airport, 74.85% land on schedule at their destination.

  • ORD is located at 10000 West O'Hare.

Chicago Midway International Airport (MDW)

  • Planning to catch a flight from Chicago Midway International Airport (MDW)? Direct Chicago to McGhee Tyson Airport (TYS) plane tickets are available from here.

  • Allegiant Air offers direct flights from Chicago to TYS out of MDW. Book your favourite window (or aisle) seat and reach your destination without any detours.

  • Allegiant Air is the top choice for bookings on the MDW to TYS route.

  • If you're looking for the most punctual carrier, go with Allegiant Air. It has an exceptional on-time performance of 80.0% for flights between Chicago Midway International Airport and McGhee Tyson Airport.

  • You can get to MDW from the centre of Chicago in about 20 minutes by car, depending on traffic. The journey by public transport takes roughly 45 minutes to cover the 19 kilometres or so.

  • Get your holiday started early with an additional night away from home. Before catching your Chicago to TYS flight, unwind in one of these hotels near Chicago Midway International Airport:

  • 77.88% of flights taking off from Chicago Midway International Airport meet their expected arrival time.

  • MDW is located at 5700 South Cicero.

Chicago Rockford International Airport (RFD)

  • The journey time to RFD from the centre of Chicago is around 4 hours 15 minutes by public transport. If you're planning to travel by car, it'll take you about 1 hour 25 minutes to cover the 137 kilometres or so.

  • Make catching an early Chicago to McGhee Tyson Airport flight the easiest part of your journey. Book a room at one of these hotels close to Chicago Rockford International Airport and get to your check-in counter with time to spare:

  • The on-time performance rating of RFD is 76.19%. To put it simply, that's how frequently flights from this airport reach their final stop as planned.

  • You'll find Chicago Rockford International Airport at 2 Airport Cir.

About McGhee Tyson Airport (TYS)

  • The last thing you need is a lengthy journey to your hotel if you're arriving on a late flight from Chicago to McGhee Tyson Airport. Make yourself comfy at one of these accommodation options near TYS instead:

  • Get on the fast track to adventure by picking up a McGhee Tyson Airport rental car. Grab your wheels from Budget, Alamo or Avis and experience the lesser-explored corners of Knoxville and beyond.

  • Lock in the lowest price by booking your vehicle around three weeks ahead of your Chicago to McGhee Tyson Airport flight.

  • TYS is located at 2055 Alcoa Highway.

How to find the cheapest flights from Chicago to McGhee Tyson Airport (TYS)

  • The cheapest price we've found for a one-way ticket from Chicago to McGhee Tyson Airport is RM201. For a return flight on this route, the best price is RM429. Depending on the availability when you book, these fares may change.

  • Booking ahead of time is often the key to scoring a cheap flight from Chicago to TYS. Fares tend to rise as demand increases, so the closer you get to departure, the more you'll likely pay.

  • If you have some flexibility with your trip dates, try using the 'Whole month' search tool. It'll give you the cheapest price across every month when searching for your Chicago to McGhee Tyson Airport ticket.

  • Save time searching for cheap plane tickets from Chicago to TYS by creating a Price Alert. We'll send you an email or push notification on the app when a new discounted fare appears.

  • Chase down a great fare on a flight from Chicago to McGhee Tyson Airport with the help of the filters. Pick your ideal departure and arrival times, airlines and number of stops. You can also sort your results by 'Best,' 'Fastest' or 'Cheapest.'

The best time to fly from Chicago to McGhee Tyson Airport (TYS)

  • July is the most popular month for flights from Chicago to McGhee Tyson Airport (TYS). Visit Knoxville in February if you'd rather avoid peak season.

  • Before locking in your Chicago to TYS plane ticket, consider the type of weather you enjoy. July is the warmest month in Knoxville, with temperatures ranging from 17ºC (63ºF) to 32ºC (90ºF).

  • If you like travelling in cooler conditions, search for a cheap ticket from Chicago to McGhee Tyson Airport in January when temperatures are between -6ºC (21ºF) and 11ºC (52ºF).

More about Knoxville

Explore more of the United States

  • You've done Knoxville, now it's time to discover more of the United States. Travel around 290 kilometres east to Charlotte to check off its leading attractions. From Bechtler Museum of Modern Art to Discovery Place and NASCAR Hall of Fame, you'll have a full itinerary ahead.

  • Around 257 kilometres west of Knoxville, Nashville is another favourite stop in the United States. Experience major highlights starting with Grand Ole Opry, Country Music Hall of Fame and Museum and The Johnny Cash Museum.

Plan the rest of your trip from Chicago to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.