Cheap flight tickets from Guayaquil to Santo Domingo

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Flight deals from Guayaquil to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Guayaquil to Santo Domingo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Guayaquil to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Guayaquil to Santo Domingo flights are currently cheapest in February.

Alternative Guayaquil to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Guayaquil to Santo Domingo? You could fly into the following airports instead.

Guayaquil to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundRM1,549
Cheapest month to flyFebruary

Finding cheap flights from Guayaquil to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Guayaquil to Santo Domingo is RM1,549. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Guayaquil to Santo Domingo. But we found flights with one or more stops from RM1,549.
As of January 2026, there are no flights flying from Guayaquil to Santo Domingo.
The cheapest month to fly from Guayaquil to Santo Domingo is usually February.
If you're flying from Guayaquil Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from RM1,549.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Guayaquil Airport to Santo Domingo on Friday, 6 February 2026.
No airlines currently offer direct flights between Guayaquil Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In January, the average temperature is usually around 25°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Copa offers the cheapest flight tickets to Santo Domingo.

Travelling from Jose Joaquin de Olmedo Airport (GYE) to Santo Domingo: what you need to know

  • The timezone in Santo Domingo is UTC-4. The city is one hour ahead of Guayaquil, where Jose Joaquin de Olmedo Airport is located.

  • To avoid rushing for your GYE to Santo Domingo flight, leave plenty of time for things like baggage drop and finding your gate. Turning up two hours before international departures and an hour before domestic flights is the standard rule.

  • If you're flying during a major holiday or another peak period, allow for even more time. A good general rule is two hours before domestic flights and up to four hours before international departures. Queues at check-in and security will be longer.

  • We make it easy to book flight tickets from GYE to Santo Domingo with a stopover. To see the options, deselect 'Direct flights only.' Then, choose a flight with a stop long enough to explore the city of your choice. Some popular stopovers include:

    • Miami International Airport (MIA)

    • El Dorado International Airport (BOG)

    • Tocumen International Airport (PTY)

  • Located around 5 kilometres from central Guayaquil, GYE can be reached in about 10 minutes by car (depending on traffic). The journey on public transport will take roughly 20 minutes.

  • Want a relaxed start to your journey? Stay near GYE. Whether you're taking an early flight from Jose Joaquin de Olmedo Airport to Santo Domingo or just don't want to be rushed, these hotels are worth a look:

  • Jose Joaquin de Olmedo Airport has an excellent on-time record, making delays less likely. Departures from GYE touch down on schedule 89.07% of the time.

How to find the cheapest flights from Jose Joaquin de Olmedo Airport (GYE) to Santo Domingo

  • RM946 is the lowest price we've seen for a one-way Jose Joaquin de Olmedo Airport to Santo Domingo flight. A return ticket right now is RM1,549. Depending on how early you book and the availability, these fares may change.

  • Booking in advance is often the key to securing a cheap flight from GYE to Santo Domingo. Prices tend to rise as demand increases, so the nearer your departure date, the more you'll likely spend on your ticket.

  • Scoring cheap tickets from Jose Joaquin de Olmedo Airport to Santo Domingo is easier if you can be flexible with your travel plans. Try using the 'Whole month' search tool to get the best prices across every month and walk away with a sweet deal.

  • There's no need to check in daily to find out if fares have dropped when you create a Price Alert. We'll update you when there's an extra saving on cheap flights from GYE to Santo Domingo.

  • Select your preferred arrival and departure times, number of stops and airlines with our filters. Then, sort the results for your flight from Jose Joaquin de Olmedo Airport to Santo Domingo by 'Cheapest,' 'Fastest' or 'Best.'

Airports in Santo Domingo

Las Americas International Airport (SDQ)

Dr. Joaquin Balaguer International Airport (JBQ)

  • Central Santo Domingo is about 19 kilometres from Dr. Joaquin Balaguer International Airport (JBQ). After your flight from Jose Joaquin de Olmedo Airport to Santo Domingo has hit the runway and you've made your way through the terminal, expect a drive of around 25 minutes.

  • Micro Hotel Condo Suites is one accommodation option within an easy drive of JBQ. Unpack your bags here after your GYE to Santo Domingo flight and then hang the 'Do not disturb' sign to get some rest.

  • Line up some great tunes and hit the open road in a Dr. Joaquin Balaguer International Airport rental car. Pick up a set of wheels from FlexWays and start exploring right away.

  • Avoid filling out forms on the spot and save time at the rental desk by having everything prearranged. Secure your ride from JBQ in advance so you can just grab the keys and go.

Best time to go to Santo Domingo

  • Plan your trip to Santo Domingo during high season if you like a busy atmosphere, but remember that prices may be higher. Alternatively, book flights from Jose Joaquin de Olmedo Airport to Santo Domingo during low season when prices are cheaper and it's less crowded.

  • Book a Jose Joaquin de Olmedo Airport to Santo Domingo flight ticket with a departure in September if you're eager to visit the city during its warmest month. Expect temperatures to range from 23ºC (73ºF) to 33ºC (91ºF).

  • February has average temperatures of between 19ºC (66ºF) and 29ºC (84ºF). Search for a cheap ticket from GYE to Santo Domingo around that time if you like cooler conditions.

More about Santo Domingo

  • After booking your flight from Jose Joaquin de Olmedo Airport to Santo Domingo, choose a hotel that combines comfort with a great location. Make one of these options your base for exploring Santo Domingo:

  • There are so many things to do and see in this city it can be tricky to work out where to start. National Palace, Alcazar de Colon and Basilica Cathedral of Santa Maria la Menor are highlights which should be on any well-planned Santo Domingo itinerary.

Explore more of Dominican Republic

  • La Romana is just one of the many cities in Dominican Republic waiting to be discovered after you've seen Santo Domingo. Around 105 kilometres away to the east, top sights here include Dye Fore Golf Course of Casa de Campo, Minitas Beach and La Estrella Park.

  • Around 161 kilometres north-west of Santo Domingo, Puerto Plata is another essential stop in Dominican Republic. Experience this destination's highlights firsthand at Fortaleza San Felipe, Teleferico Puerto Plata Cable Car and Malecon Puerto Plata.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.