Cheap flight tickets from Indianapolis to Knoxville

Compare Indianapolis to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Indianapolis Airport to Knoxville Airport

Looking for a cheap last-minute deal or the best return flight from Indianapolis Airport to Knoxville Airport? If you want to travel next month, return fares start from RM1,228. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Indianapolis to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Indianapolis to Knoxville flights are currently cheapest in May.

Indianapolis to Knoxville: Alternative routes

Compare routes from Indianapolis to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Indianapolis to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundRM540
Cheapest month to flyMay

Finding cheap flights from Indianapolis to Knoxville: Frequently asked questions

The best price we found for a return flight from Indianapolis to Knoxville is RM1,228. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Indianapolis to Knoxville. But we found flights with one or more stops from RM1,228.
As of March 2026, there are no flights flying from Indianapolis to Knoxville.
The cheapest month to fly from Indianapolis to Knoxville is usually April.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Indianapolis Airport to Knoxville Airport on Monday, 27 April 2026.
No airlines currently offer direct flights between Indianapolis Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Knoxville.

Travelling from Indianapolis International Airport (IND) to McGhee Tyson Airport (TYS): what you need to know

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are tried-and-true travel tips. Get to the airport on time to catch your IND to TYS flight.

  • Travelling during a peak time like July? Major public holidays and other popular seasons can lead to longer queues and delays at check-in and security. Be extra cautious and get there up to four hours before international flights and two hours before a domestic departure.

  • If you'd like to split up your journey, simply deselect 'Direct flights only' when searching for your ticket from Indianapolis International Airport to McGhee Tyson Airport. These are the most popular stopovers between IND and TYS:

    • Hartsfield-Jackson Atlanta International Airport

    • Charlotte Douglas International Airport

    • Detroit Metropolitan Wayne County Airport

How to find the cheapest flights from Indianapolis International Airport (IND) to McGhee Tyson Airport (TYS)

  • RM540 is the best price for a one-way Indianapolis International Airport to McGhee Tyson Airport flight. Return flights start at RM1,228. These prices may change depending on availability.

  • To get your hands on cheap tickets from IND to TYS, book early. Airlines typically offer their most competitively priced fares when flights are first made available.

  • Getting cheap flights from Indianapolis International Airport to McGhee Tyson Airport is easier if you're flexible with your travel dates. Use the 'Whole month' function to see the lowest prices across the month and land a great deal.

  • You won't have to check back in every day to find out if fares have gone down when you create a Price Alert. We'll notify you the moment a special offer becomes available on cheap flights from IND to TYS.

  • Tailor your trip with filters. Choose your ideal arrival and departure times, airlines and total journey duration. You can also sort results by 'Cheapest,' 'Best' or 'Fastest' flights from Indianapolis International Airport to McGhee Tyson Airport.

Handy information about Indianapolis International Airport (IND)

  • IND is located at 7800 Col. H. Weir Cook Memorial Drive.

  • When it comes to Indianapolis International Airport's on-time performance, 79.86% of flights arrive within the scheduled timeframe.

  • Central Indianapolis to Indianapolis International Airport is approximately 24 kilometres. Depending on traffic, it'll take you about 25 minutes to get there if you're driving, ride-sharing or catching a cab.

  • Expect a journey time of around 1 hour when using public transport.

  • Get your journey off to a relaxed start by staying near IND. Whether you're boarding an early flight from Indianapolis International Airport to McGhee Tyson Airport or want to avoid feeling rushed, these stays are ideal:

Arriving at McGhee Tyson Airport (TYS)

  • If you have a late Indianapolis International Airport to McGhee Tyson Airport flight, few things top the convenience of being near the terminal. Grab your suitcases from the carousel and then be showered and snoozing soon after at one of these accommodation options near TYS:

  • Pick up a McGhee Tyson Airport rental car and explore Knoxville and beyond with your own wheels. Budget, Alamo and Avis are top outlets to choose from here.

  • To lock in the lowest price, book your vehicle from McGhee Tyson Airport about three weeks before you set off.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • TYS is located at 2055 Alcoa Highway.

  • McGhee Tyson Airport is approximately 23 kilometres from central Knoxville. Driving there takes about 20 minutes.

When to fly to McGhee Tyson Airport (TYS)

  • It's time to pick your dates for your flight from Indianapolis International Airport to McGhee Tyson Airport. July is the most popular month to visit Knoxville. If you want a quieter vibe, go in February.

  • Before locking in your flight from Indianapolis International Airport to McGhee Tyson Airport, think about the type of weather you enjoy. July is the warmest month in Knoxville, with the temperature ranging from 17ºC (63ºF) to 32ºC (90ºF).

  • January sees average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Search for cheap tickets from IND to TYS sometime then if you want to travel in cooler conditions.

Explore more of United States

  • Columbus is just one of the many places in United States waiting to be discovered once you've seen Knoxville. Around 451 kilometres away to the north, its top attractions include Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.

  • Around 467 kilometres north-west of Knoxville, Indianapolis is another favourite stop in United States. Start your sightseeing at The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.