Skyscanner

Cheap flight tickets from Raleigh / Durham to St Louis

Compare Raleigh / Durham to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Flight deals from Raleigh / Durham to St Louis

Looking for a cheap last-minute deal or the best return flight from Raleigh / Durham to St Louis? Find the lowest prices on one-way and return tickets right here.
St Louis.RM602 per passenger.Departing Thu, 2 Oct, returning Mon, 6 Oct.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Thu, 2 Oct, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Mon, 6 Oct, arriving in Raleigh / Durham.Price includes taxes and charges.From RM602, select.
St Louis.RM602 per passenger.Departing Mon, 29 Sep, returning Mon, 6 Oct.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Mon, 29 Sep, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Mon, 6 Oct, arriving in Raleigh / Durham.Price includes taxes and charges.From RM602, select.
St Louis.RM603 per passenger.Departing Fri, 24 Oct, returning Sat, 1 Nov.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Fri, 24 Oct, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Sat, 1 Nov, arriving in Raleigh / Durham.Price includes taxes and charges.From RM603, select.
St Louis.RM774 per passenger.Departing Thu, 25 Sep, returning Mon, 29 Sep.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Thu, 25 Sep, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Mon, 29 Sep, arriving in Raleigh / Durham.Price includes taxes and charges.From RM774, select.
St Louis.RM1,153 per passenger.Departing Fri, 5 Dec, returning Sun, 7 Dec.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Fri, 5 Dec, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Sun, 7 Dec, arriving in Raleigh / Durham.Price includes taxes and charges.From RM1,153, select.
St Louis.RM1,328 per passenger.Departing Wed, 5 Nov, returning Sun, 9 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Raleigh / Durham on Wed, 5 Nov, arriving in St Louis.Inbound indirect flight with Delta, departs from St Louis on Sun, 9 Nov, arriving in Raleigh / Durham.Price includes taxes and charges.From RM1,328, select.
St Louis.RM1,440 per passenger.Departing Thu, 16 Oct, returning Mon, 20 Oct.Return flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Raleigh / Durham on Thu, 16 Oct, arriving in St Louis.Inbound direct flight with Southwest Airlines departs from St Louis on Mon, 20 Oct, arriving in Raleigh / Durham.Price includes taxes and charges.From RM1,440, select.
St Louis.RM1,446 per passenger.Departing Thu, 6 Nov, returning Tue, 11 Nov.Return flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Raleigh / Durham on Thu, 6 Nov, arriving in St Louis.Inbound direct flight with Southwest Airlines departs from St Louis on Tue, 11 Nov, arriving in Raleigh / Durham.Price includes taxes and charges.From RM1,446, select.

Find the cheapest month to fly from Raleigh / Durham to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Raleigh / Durham to St Louis flights are currently cheapest in October.
Sep
from RM774
Oct
from RM602
Nov
from RM1,328
Dec
from RM1,153
Jan
from RM1,747
Feb
from RM1,882
Mar
Find prices
Apr
Find prices
May
from RM1,878
Jun
Find prices
Jul
from RM1,878
Aug
Find prices

Direct flights from Raleigh / Durham to St Louis

Raleigh / Durham to St Louis: Alternative routes

Compare routes from Raleigh / Durham to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Durham to St Louis: Flight information

The things to know before you go.
Cheapest flight foundRM602
Cheapest month to flySeptember
Average flight time2 hrs, 13 mins
Most popular airlineSouthwest Airlines
Average flights per week13

Finding cheap flights from Raleigh / Durham to St Louis: Frequently asked questions

The best price we found for a return flight from Raleigh / Durham to St Louis is RM602. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 13 minutes is the average flight time from Raleigh / Durham to St Louis.
Southwest Airlines flies direct from Raleigh / Durham to St Louis.
As of September 2025, there are 13 flights per week flying from Raleigh / Durham to St Louis.
The cheapest month to fly from Raleigh / Durham to St Louis is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Raleigh / Durham Airport to St Louis Airport on Monday, 29 September 2025.
Yes – the average flight time is 2 hours and 13 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Frontier Airlines and Southwest Airlines offer the cheapest flight tickets to St Louis.

Flying from Raleigh-Durham International Airport (RDU) to Lambert-St. Louis International Airport (STL): what you need to know

  • Around 2 hours 15 minutes is how long you can expect to be travelling on a direct flight from Raleigh-Durham International Airport to Lambert-St. Louis International Airport.

  • St Louis is one hour behind Durham and observes the UTC-5 timezone.

  • Choose from nine weekly Raleigh-Durham International Airport to Lambert-St. Louis International Airport flights. The 06:45 departure with Southwest Airlines is the earliest flight available. Southwest Airlines operates the latest service of the day at 20:55.

  • For a smooth journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This will give you enough time to catch your RDU to STL flight.

  • During popular months such as July, it's best to get to the airport even earlier. Arrive two hours before a domestic departure and four hours ahead of an international flight when you travel during a high season in general.

  • Southwest Airlines offers direct flights from Raleigh-Durham International Airport to Lambert-St. Louis International Airport. Book with this popular airline, then get ready to tick off the sights in St Louis — and maybe even more of United States if time allows.

  • Most travellers choose to travel with Southwest Airlines on this route.

  • Southwest Airlines is the most punctual carrier offering RDU to STL flights. A reliable 81.65% of its services on this route arrive without delay.

  • If you'd like to explore another city along the way, simply deselect 'Direct flights only' when searching for your ticket from Raleigh-Durham International Airport to Lambert-St. Louis International Airport. These are the top stopovers between RDU and STL:

    • Charlotte Douglas International Airport

    • Hartsfield-Jackson Atlanta International Airport

    • Nashville International Airport

How to find the cheapest flights from Raleigh-Durham International Airport (RDU) to Lambert-St. Louis International Airport (STL)

  • The cheapest price we've found for a one-way Raleigh-Durham International Airport to Lambert-St. Louis International Airport flight is RM302. A return plane ticket right now is RM602. Depending on the availability when you book, these fares could change.

  • To score cheap tickets from RDU to STL, reserve your trip seven months ahead of your departure date.

  • Schedule your trip for June. That's the cheapest month for flights from Raleigh-Durham International Airport to Lambert-St. Louis International Airport. If your travel dates are flexible, use the 'Whole month' tool to see the lowest price across each month.

  • Cut down on the time spent looking for cheap flights from RDU to STL by creating a Price Alert. You'll receive an email or notification through the app when a new discounted fare appears.

  • Lock in the perfect flight for you by using the filters. To see the 'Best,' 'Cheapest' or 'Fastest' flights from Raleigh-Durham International Airport to Lambert-St. Louis International Airport, use the 'Sort by' function. You can also filter by airline, arrival and departure times, and journey duration.

Handy information about Raleigh-Durham International Airport (RDU)

  • Raleigh-Durham International Airport earns top marks for its on-time performance. 80.09% of flights that depart RDU arrive at their destination on time.

  • To reach Raleigh-Durham International Airport from central Durham, it'll take around 20 minutes if you're planning to drive. Of course, this depends on traffic conditions. It's approximately 23 kilometres from the airport to the city centre.

  • Planning to take public transport? You can expect a journey time of around 1 hour 10 minutes.

  • Get your trip off to a relaxed start by staying near RDU. Whether you're catching an early flight from Raleigh-Durham International Airport to Lambert-St. Louis International Airport or just don't want to be rushed, these hotels are the answer:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • STL is located at 10701 Lambert International Blvd..

  • Lambert-St. Louis International Airport to the centre of St Louis has a drive time of about 20 minutes. It's approximately 26 kilometres away.

  • It typically takes 35 minutes when travelling by public transport.

When to fly to Lambert-St. Louis International Airport (STL)

  • It's time to work out your dates for your flight from Raleigh-Durham International Airport to Lambert-St. Louis International Airport. July is the busiest month to visit St Louis. If you prefer a quieter vibe, go in April.

  • The warmest month in St Louis is July, with the temperature ranging between 17ºC (63ºF) and 33ºC (91ºF). Lock in your flights from Raleigh-Durham International Airport to Lambert-St. Louis International Airport in this month if you like this kind of weather.

  • Search for cheap tickets from RDU to STL in January if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between -8ºC (18ºF) and 7ºC (45ºF) on average.

Explore more of United States

  • You've done St Louis, now it's time to discover more of United States. Journey around 418 kilometres north-east to Chicago to tick off its top sights. From Millennium Park to Art Institute of Chicago and LandShark Beer Garden at Navy Pier, your itinerary will be busy.

  • If you want to check out another well-known destination in United States, head for Indianapolis, roughly 370 kilometres east of St Louis. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are key reasons to visit.

Plan the rest of your trip from Durham to St Louis

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.