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Cheap flight tickets from Chicago to Panama City

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Flight deals from Chicago to Panama City

Looking for a cheap last-minute deal or the best return flight from Chicago to Panama City? If you want to travel next month, return fares start from RM1,129. Find the lowest prices on one-way and return tickets right here.
Panama City.RM1,129 per passenger.Departing Sun, 19 Apr, returning Thu, 23 Apr.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Chicago O'Hare International on Sun, 19 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 23 Apr, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,129, select.
Panama City.RM1,140 per passenger.Departing Sun, 26 Apr, returning Sat, 2 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Chicago O'Hare International on Sun, 26 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 2 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM1,140, select.
Panama City.RM2,350 per passenger.Departing Sun, 31 May, returning Tue, 9 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Sun, 31 May, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Tue, 9 Jun, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,350, select.
Panama City.RM2,418 per passenger.Departing Wed, 8 Jul, returning Wed, 15 Jul.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Wed, 8 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Wed, 15 Jul, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,418, select.
Panama City.RM2,451 per passenger.Departing Wed, 29 Jul, returning Mon, 3 Aug.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Wed, 29 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Mon, 3 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,451, select.
Panama City.RM2,451 per passenger.Departing Sat, 13 Jun, returning Sat, 20 Jun.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Sat, 13 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sat, 20 Jun, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,451, select.
Panama City.RM2,461 per passenger.Departing Sun, 2 Aug, returning Fri, 7 Aug.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Sun, 2 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 7 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,461, select.
Panama City.RM2,461 per passenger.Departing Fri, 25 Sep, returning Tue, 29 Sep.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Fri, 25 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 29 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,461, select.
Panama City.RM2,473 per passenger.Departing Fri, 22 Jan, returning Sat, 30 Jan.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 22 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sat, 30 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,473, select.
Panama City.RM2,473 per passenger.Departing Thu, 23 Jul, returning Sun, 26 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Thu, 23 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 26 Jul, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,473, select.
Panama City.RM2,473 per passenger.Departing Fri, 14 Aug, returning Mon, 17 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 14 Aug, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 17 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,473, select.
Panama City.RM2,473 per passenger.Departing Wed, 29 Jul, returning Mon, 3 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Wed, 29 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 3 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,473, select.
Panama City.RM2,473 per passenger.Departing Fri, 25 Sep, returning Fri, 2 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 25 Sep, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Fri, 2 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,473, select.
Panama City.RM2,482 per passenger.Departing Wed, 6 May, returning Sun, 10 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Chicago Midway on Wed, 6 May, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Sun, 10 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,482, select.
Panama City.RM2,483 per passenger.Departing Thu, 1 Oct, returning Sun, 1 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Thu, 1 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 1 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,483, select.
Panama City.RM2,483 per passenger.Departing Mon, 29 Jun, returning Sun, 5 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Mon, 29 Jun, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 5 Jul, arriving in Chicago O'Hare International.Price includes taxes and charges.From RM2,483, select.

Find the cheapest month to fly from Chicago to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Panama City flights are currently cheapest in April.
Mar
from RM2,891
Apr
from RM1,129
May
from RM2,482
Jun
from RM2,451
Jul
from RM2,418
Aug
from RM2,461
Sep
from RM2,461
Oct
from RM2,737
Nov
from RM3,539
Dec
from RM3,321
Jan
from RM2,473
Feb
Find prices

Direct flights from Chicago to Panama City

Alternative Chicago to Panama City routes

Looking for the cheapest, fastest or easiest route from Chicago to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
Search flights

Balboa

5km from central Panama City
from RM3,720
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from RM1,129
Search flights

Chicago to Panama City: Flight information

The things to know before you go.
Cheapest flight foundRM1,129
Cheapest month to flyApril
Average flight time5 hrs, 22 mins
Most popular airlineCopa
Average flights per week49

Check out these Panama City hotels

Ready to plan your stay? Other travellers rate these Panama City hotels for cleanliness, service and location.
SERENADE Lodging Rooms
1.83 km from city centre
RM190
Per night
Eden`s Garden Hostel
1.64 km from city centre
RM164
Per night
Hostal Yoha
1.77 km from city centre
RM148
Per night
SERENADE Lodging Rooms
1.83 km from city centre
RM190
Per night
Eden`s Garden Hostel
1.64 km from city centre
RM164
Per night
Hostal Yoha
1.77 km from city centre
RM148
Per night
Explore top-rated hotels

Finding cheap flights from Chicago to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Chicago to Panama City is RM1,129. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 22 minutes is the average flight time from Chicago to Panama City.
Copa, United and EVA Air fly direct from Chicago to Panama City.
As of March 2026, there are 441 flights per week flying from Chicago to Panama City.
The cheapest month to fly from Chicago to Panama City is usually April.
If you're flying from Chicago, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from RM1,129.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Panama City on Sunday, 19 April 2026.
Yes – the average flight time is 5 hours and 22 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
The cheapest airline that flies to Panama City is Avianca. And the cheapest airline that flies to Balboa Airport is Copa.

Flying from Chicago to Panama City: what you need to know

  • There are two main airports you can take off from in Chicago. Check out your options departing from O'Hare International Airport (ORD) or Chicago Midway International Airport (MDW) when reserving your flight from Chicago to Panama City.

  • Tocumen International Airport (PTY) and Panama Pacifico Airport (BLB) are Panama City's chief entry points.

  • Around 5 hours 30 minutes is how long you can expect to be travelling on a direct Chicago to Panama City flight.

  • Chicago and Panama City share the same timezone, UTC-5.

  • The busiest route for flights from Chicago to Panama City is from O'Hare International Airport (ORD) to Tocumen International Airport (PTY). There are 11 weekly services between these two airports. If you'd like to be on your way as soon as possible, the earliest flight from ORD to PTY is the 01:07 Copa Airlines service. If you prefer travelling later, the final scheduled service is at 15:10 with Copa Airlines.

  • Leave enough time to catch your Chicago to Panama City flight. A good rule of thumb is to arrive two hours before international departures and an hour ahead for domestic flights.

  • You'll likely experience longer lines during popular months such as August. Arriving up to four hours in advance for international flights and two hours for a domestic departure is a smart move.

How to find the cheapest flights from Chicago to Panama City

  • Lock in cheap Chicago to Panama City flights by booking three months ahead. According to our research, that's the ideal time frame for finding the biggest deals.

  • The best month for finding cheap plane tickets from Chicago to Panama City is June. Use the 'Whole month' tool to compare flight prices, then choose the dates offering the lowest fares.

  • Cut down on the time spent looking for cheap flights from Chicago to Panama City by setting up a Price Alert. We'll send you an email or push notification on the app when a new discounted fare appears.

  • Pick your preferred departure and arrival times, number of stops and airlines with the filters. Or sort your Chicago to Panama City flight results by 'Fastest,' 'Best' or 'Cheapest.'

Flying from Chicago

O'Hare International Airport (ORD)

  • If you're looking for a direct flight from Chicago to Panama City, you can depart from O'Hare International Airport (ORD). Fly from ORD to Tocumen International Airport (PTY) without making any stops.

  • Check out the promotions with Copa Airlines. This airline offers direct Chicago to Panama City plane tickets out of ORD.

  • We make it a breeze to find a Chicago to Panama City flight with a stopover. To see the options departing from O'Hare International Airport, uncheck 'Direct flights only.' Then, choose a flight that has a stop long enough to tour the city of your choice. Top stopovers include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Miami International Airport (MIA)

    • Raleigh-Durham International Airport (RDU)

  • ORD is about 26 kilometres from central Chicago. If you're catching a cab, driving or ride-sharing from the centre, it'll take you 35 minutes or so to get there, depending on the traffic. If you're planning to take public transport, expect the travel time to be around 55 minutes.

  • Searching for a handy hotel close to O'Hare International Airport? If you're catching an early flight from Chicago to Panama City, these accommodation options will have you sleeping moments from your departure gate:

  • 74.85% of flights that depart O'Hare International Airport touch down at their destination on schedule.

  • The address for ORD is 10000 West O'Hare.

Chicago Midway International Airport (MDW)

  • Get the most out of your holiday with a stopover on your Chicago to Panama City flight. Visit friends or family or tick another city off your list. Whatever you want to do, check out these stops between Chicago Midway International Airport and Panama City:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Orlando International Airport (MCO)

    • Raleigh-Durham International Airport (RDU)

  • MDW is around 14 kilometres from central Chicago. It'll take you 20 minutes or so to get to the airport in a car from the city centre. Public transport takes roughly 45 minutes.

  • Start your holiday sooner with an extra night away from home. Before your flight from Chicago to Panama City, take it easy in one of these hotels near Chicago Midway International Airport:

  • When it comes to keeping flights on track, Chicago Midway International Airport has an on-time arrival performance of 78%.

  • MDW is located at 5700 South Cicero.

Arriving in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) is approximately 16 kilometres from central Panama City. If you're catching a cab or a ride-share, the drive takes roughly 20 minutes.

  • It usually takes 1 hour 5 minutes to get there on public transport.

  • If you're coming in on a late flight from Chicago to Panama City, nothing beats the convenience of staying near the terminal. Pick up your bags from the carousel and then be showered and snoozing soon after at one of these accommodation options near PTY:

  • Travel at your own speed with a Tocumen International Airport rental car. Book your wheels from Avis, Dollar or MEX and venture far and wide through Panama City and beyond.

  • Secure the lowest price by reserving your ride from Tocumen International Airport around three weeks in advance of your trip.

Marcos A. Gelabert International Airport (PAC)

  • After your flight from Chicago to Panama City has hit the runway, you can reach the city centre in around 5 minutes by car. Central Panama City is approximately 2 kilometres from Marcos A. Gelabert International Airport (PAC).

  • If you hop on public transport, the ride to the centre takes 25 minutes or so.

  • You'll find some great places to call home for the night near BLB. Settle in and get cosy after your Chicago to Panama City flight at one of these well-located options:

  • The quickest way to get to where you're going is with a Marcos A. Gelabert International Airport rental car. Collect your wheels from Thrifty, Avis or Alamo and set off in the blink of an eye.

  • Lock in the lowest price by reserving your ride from PAC three weeks ahead of time. You'll also have access to a wider range of vehicles.

Panama Pacifico Airport (BLB)

  • Make your way to the city centre after your flight from Chicago to Panama City has landed. Central Panama City is around 11 kilometres from Panama Pacifico Airport (BLB) and takes roughly 20 minutes to reach by cab or ride-share.

  • Whether you'd like a zippy compact for a solo getaway or an SUV to fit the family, you'll find the perfect Panama Pacifico Airport rental car for you. Explore the range of wheels available here from providers such as Sixt, Dollar and Thrifty.

  • Around one week ahead of your flight from Chicago to Panama City is the ideal time to book your vehicle from BLB. You're more likely to find a cheaper rate or pick up some early bird promotions.

Best time to go to Panama City

  • February is the quietest month for flights from Chicago to Panama City, while June is the most popular. Find the ideal time to visit Panama City based on whether you prefer a laid-back vibe or a more bustling atmosphere.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Book your Chicago to Panama City ticket then if that's your definition of good weather.

  • If you want to travel in cooler conditions, search for a cheap flight from Chicago to Panama City in February when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • When it comes to looking for somewhere to rest your head, you'll find the most popular stays in Panama City right here. Explore these hotels as soon as you've locked in your flight from Chicago to Panama City:

  • All great holidays should include a little sightseeing. Panama Canal Museum, Casco Viejo and Cinta Costera are essential stops on your Panama City itinerary.

Explore more of Panama

  • San Miguelito is just one of the many cities in Panama waiting to be explored once you've taken in the sights of Panama City. Around 6 kilometres to the north, top sights here include Iglesia Cristo Luz del Mundo, IDMJI SAN MIGUELITO and Iglesia Bautista Independiente Emanuel.

  • Juan Díaz is another favourite destination in Panama and is around 11 kilometres north-east of Panama City. No trip is complete without experiencing Malecon Costa Del Este, El Patio Human Friendly and Parque Los Robles Sur.

Plan the rest of your trip from Chicago to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.